N-Hydroxydiamine — vielseitige Bausteine für Wirkstoffsynthesen
- An enzymatic cascade from ω-amino amino acids towards monohydroxylated α,ω-diamines gives highly interesting materials for processing into fine chemicals. With two simple UV-vis spectroscopy-based screening methods, enzyme candidates with a compatibility window to perform a three-enzyme cascade from lysine and ornithine to the desired products were identified. The results give first insight into the feasibility of the desired cascade and put handles on future reaction engineering tasks.
| Author: | Artur MaierGND, Sarah WanselGND, Álvaro Gómez BaraibarORCiDGND, Carolin MüggeORCiDGND, Dirk TischlerORCiDGND |
|---|---|
| URN: | urn:nbn:de:hbz:294-80484 |
| DOI: | https://doi.org/10.1007/s12268-020-1374-6 |
| Parent Title (German): | BIOspektrum |
| Publisher: | Springer Nature |
| Place of publication: | Berlin |
| Document Type: | Article |
| Language: | German |
| Date of Publication (online): | 2021/04/29 |
| Date of first Publication: | 2020/05/14 |
| Publishing Institution: | Ruhr-Universität Bochum, Universitätsbibliothek |
| Volume: | 26 |
| First Page: | 330 |
| Last Page: | 332 |
| Note: | Dieser Beitrag ist auf Grund des DEAL-Springer-Vertrages frei zugänglich. |
| Institutes/Facilities: | Lehrstuhl für Pflanzenphysiologie, Nachwuchsgruppe Mikrobielle Biotechnologie |
| Dewey Decimal Classification: | Naturwissenschaften und Mathematik / Biowissenschaften, Biologie, Biochemie |
| open_access (DINI-Set): | open_access |
| faculties: | Fakultät für Biologie und Biotechnologie |
| Licence (German): |  Creative Commons - CC BY 4.0 - Namensnennung 4.0 International |
